Phsopho-PKCa (pT638)

来自 : 发布时间：2025-11-18

货号：	1195-1
是否单克隆：	否
抗体英文名：	Phsopho-PKCa (pT638)
供应商：	泰泽瑞达
级别：	Clone ID:E195
保存条件：	-20
宿主：	Human, Mouse, Rat
数量：	大量
应用范围：	WB, IHC, ICC, IP
适应物种：	Human, Mouse, Rat
抗原来源：	Rabbit Mab
规格：	100µl

scientific background:Activation of PKC plays a crucial role in tranducing signals for a variety of cellular responses, including tumor proliferation (1). PKC isoforms have been classified into three groups: classical, novel, and atypical. Members of these three PKC groups contain an autoinhibitory domain that binds to the substrate binding site in the catalytic domain, preventing its activation in the absence of cofactors or activators (2,3). The activity of PKC is under the control of three distinct phosphorylation events, including that of the Thr641 autophosphorylation site (4).；innunogen:A synthetic phospho-peptide corresponding to residues surrounding Thr638 of human PKC? was used as immunogen. The antibody only detects PKC alpha phosphorylated on Threonine 638. Predicted to cross-react with rat, bovine and chicken, based on sequence hom 温馨提示：不可用于临床治疗。